Rousso Adams Facial Plastic Surgery is continually exploring the next frontier in skin repair, as our patients deserve treatments grounded in real science, not fleeting trends. Guided by the combined expertise of triple-board-certified Dr. Daniel Rousso and double-board-certified Dr. Austin Adams, our facial-focused practice has long championed regenerative therapies that help skin heal, strengthen, and transform from within. That mission is precisely why we’re so excited about one of the most talked-about breakthroughs in modern aesthetics: Salmon DNA (PDRN) microneedling, a treatment that brings cellular rejuvenation to an entirely new level.
The Science Behind Salmon DNA (PDRN)
Salmon DNA, known scientifically as polydeoxyribonucleotide (PDRN), has gained international recognition for its pro-healing properties. Research indicates that PDRN promotes cellular repair by activating the body’s adenosine A2A receptors—specialized signaling pathways that play a central role in how skin responds to injury, inflammation, and stress.
When these receptors are stimulated, several beneficial processes occur simultaneously:
- Enhanced tissue regeneration: A2A activation encourages fibroblasts—your skin’s collagen-producing cells—to proliferate and work more efficiently, supporting stronger, healthier tissue formation.
- Reduced inflammation: A2A signaling helps calm overactive inflammatory responses, which is essential for improving redness, irritation, and post-inflammatory pigmentation.
- Improved blood flow and oxygenation: These receptors are involved in vascular regulation, helping deliver nutrients and oxygen to damaged areas so they can repair more effectively.
- Accelerated wound healing: By promoting both cellular growth and anti-inflammatory balance, activation of the A2A receptor helps the skin recover faster and with better quality.
In other words, PDRN doesn’t just sit on the surface—it actively communicates with your skin’s biological repair systems.
PDRN is extracted through a pharmaceutical-grade purification process from salmon sperm, resulting in a clean, biocompatible compound. Because of its high purity and structural similarity to human DNA, the risk of allergic reaction is extremely low.
What Makes the Salmon Sperm Microneedling Facial Different?
Our Salmon Sperm Microneedling Facial, also known as the PDRN Facial, combines two proven regenerative technologies.
Microneedling creates controlled, microscopic punctures which encourage:
- Increased collagen and elastin production
- Improved cellular turnover
- Enhanced absorption of targeted serums
Next, highly purified salmon DNA is applied topically to deliver:
- Deep hydration
- Collagen-stimulating action
- Anti-inflammatory benefits
- Accelerated tissue renewal
What to Expect During Treatment
Your session begins with a detailed consultation with our aesthetic team to ensure the treatment is tailored to your specific skin needs. After cleansing and preparation:
- Microneedling is performed to create micro-injuries and open pathways for serum penetration
- PDRN serum is applied, allowing the highly active DNA fragments to sink deeply into the skin and initiate regeneration
Keep the following in mind:
- Most treatments take 60–90 minutes
- Mild redness similar to a light sunburn may occur for a day or two
- While some patients notice improvement after a single session, the most transformative results typically emerge after a series of treatments
- Pricing varies depending on your custom care plan and the number of recommended sessions
- Most patients can expect $350–$800 per session, with package pricing available
Experience Cellular-Level Renewal With Rousso Adams
Salmon DNA may be the newest buzz in aesthetics, but the science behind PDRN is anything but fleeting. With its unparalleled ability to support true cellular repair, PDRN microneedling offers a modern, biologically intelligent approach to revitalizing the skin from within—exactly the kind of advanced, evidence-based treatment that defines our practice.
With decades of combined experience, board-certified surgical leadership, and a whole team of medical aestheticians and nurses trained in advanced regenerative therapies, we deliver a level of precision and patient care unmatched in the region.
Our practice combines the luxuries of a concierge-style experience with academically rigorous, science-backed treatments. Every aspect of care is designed to be safe, comfortable, and deeply restorative.
If you’re ready to experience the rejuvenating power of regenerative skincare guided by Birmingham’s leading facial specialists, we invite you to take the next step. Schedule your consultation with Rousso Adams Facial Plastic Surgery today.
Sources
- Polydeoxyribonucleotide: A promising skin anti-aging agent - ScienceDirect
- Anti‐inflammatory effect of polydeoxyribonucleotides (PDRN) extracted from red alga (Porphyra sp.) (Ps‐PDRN) in RAW 264.7 macrophages stimulated with Escherichia coli lipopolysaccharides
- Comparison of Polynucleotide and Polydeoxyribonucleotide in Dermatology: Molecular Mechanisms and Clinical Perspectives - PMC